Want to see Comment
W~Wish (TV)
Sugar: A Little Snow Fairy (TV)
Spirited Away (movie)
Sayonara, Zetsubou-Sensei (TV)
Neon Genesis Evangelion (TV) It's like Akira except in series form; everyone has to see this at some point too.
Martian Successor Nadesico (TV)
Hidamari Sketch (TV)
Grave of the Fireflies (movie)
Excel Saga (TV) Same as AzuDai. I'm amazed the kami of anime hasn't hit me with a bolt of lighting yet or something for not watching these two shows.
Azumanga Daioh (TV) Looking at the overwhelming presence of comedic serieses in my list, it boggles the mind as to why I haven't seen what is quite possibly the most well-known comedic series of all time.
Akira (movie) Because everyone has to see Akira at some point. Come one, it's freakin' Akira.