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The title came from food poisoning caused by ciguatoxin, a toxin present in many microorganisms living in tropical waters, often accumulated all the way to the top of the food chain through biomagnification. The author used this title to symbolize the lives of his characters are undergoing a slow but accumulating form of self-inflicted poisoning.
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Anime Programming in the US
Making a Living in Manga in Japan with Felipe Smith
Lost in Translation