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This is simply anime that makes me feel better when I watch it.
Most of these are comedies and those that are serious have an optimistic story and usually a happy ending.

Feel-good anime Rating
(The) Adventures of Mini-Goddess (TV) Very good
Ai Yori Aoshi (TV) Excellent
Ai Yori Aoshi ~Enishi~ (TV) Very good
All Purpose Cultural Cat Girl Nuku Nuku (OAV) Excellent
All Purpose Cultural Cat Girl Nuku Nuku (TV) Very good
Angel Tales (TV) Very good
Angelic Layer (TV) Excellent
Aria - The Natural (TV) Excellent
Aria the Animation (TV) Excellent
Aria the Origination (TV) Excellent
Aria the OVA ~Arietta~ Excellent
Azumanga Daioh (TV) Excellent
Bamboo Blade (TV) Excellent
Cardcaptor Sakura (TV) Masterpiece
Cat Planet Cuties (TV) Very good
Cat Planet Cuties (OAV) Very good
Chobits (TV) Excellent
Comic Party (TV) Very good
Comic Party: Revolution (TV) Very good
Daphne in the Brilliant Blue (TV) Excellent
Disgaea (TV) Very good
Doki Doki School Hours (TV) Good
Fancy Lala (TV) Masterpiece
Figure 17 (TV) Masterpiece
Full Metal Panic? Fumoffu (TV) Very good
Ghost Stories (TV) Excellent
Girls Bravo (TV) Excellent
Girls und Panzer (TV) Excellent
Heaven's Lost Property (TV) Excellent
Heaven's Lost Property Forte (TV) Excellent
Heaven's Lost Property: Project Pink (OAV) Very good
Hidamari Sketch (TV)
High School DxD (TV) Very good
K-ON! (TV) Excellent
K-ON! (movie) Excellent
K-ON!! (TV 2) Masterpiece
Kamichu! (TV) Masterpiece
Kamisama Kiss (TV) Very good
Kanokon: The Girl Who Cried Fox (TV) Very good
Kanokon: The Girl Who Cried Fox (OAV) Very good
Kiki's Delivery Service (movie) Excellent
Koihime Musō (TV) Excellent
A Little Snow Fairy Sugar (TV) Excellent
Lucky Star (TV) Excellent
Magical Meow Meow Taruto (TV) Very good
Magikano (TV) Very good
Mao-chan (TV) Very good
Mayo Chiki! (TV) Very good
(The) Melancholy of Haruhi-chan Suzumiya (ONA) Excellent
My Neighbor Totoro (movie) Masterpiece
Negima! (TV) Excellent
Negima!? (TV) Very good
Ninja Nonsense (TV) Excellent
Omishi Magical Theater Risky Safety (TV) Very good
Pani Poni Dash! (TV) Excellent
Panyo Panyo Di Gi Charat (TV) Very good
Petite Princess Yucie (TV) Excellent
Rumiko Takahashi Anthology (TV) Excellent
Saint Tail (TV) Excellent
School Rumble (TV) Excellent
School Rumble: 2nd Semester (TV) Excellent
Seven of Seven (TV) Good
Shin Koihime Musō (TV) Excellent
Shin Koihime Musō: Otome Tairan (TV) Excellent
Shingu: Secret of the Stellar Wars (TV) Excellent
Solty Rei (TV) Excellent
Someday's Dreamers (TV) Very good
Spirited Away (movie) Masterpiece
Stellvia (TV) Masterpiece
Summer Wars (movie) Excellent
Tears to Tiara (TV) Excellent
To Heart (TV) Excellent
Tokyo Mew Mew (TV) Very good
Ultra Maniac (TV) Excellent
Wandaba Style (TV) Good
Wedding Peach (TV) Excellent
Wedding Peach DX (OAV) Excellent
You're Under Arrest (TV) Excellent
You're Under Arrest Specials Excellent